Dr. Osei Kwame Despite is one of Ghana’s most admired business moguls and philanthropists. As the CEO of the Despite Group of Companies, his rise from humble beginnings to becoming a Ghanaian billionaire is nothing short of inspiring.
Known for his low-key but luxurious lifestyle, Dr. Osei Kwame Despite’s wealth is often revealed through his taste in cars, property, and generous acts.
The Ghanaian business titan’s riches are the stuff of legend, but hearing and seeing it in its full glory are two entirely different things.
Despite being known to have started making money from his cassette-selling business.
Before the days of CDs, the businessman was a distributor of Ghanaian films.
His joint in Accra’s Opera Square was the hottest joint to get the latest Ghanaian film.
The Ghanaian millionaire is not on record as having granted any media interview to talk about his acquisition of wealth.
However, it is said that his cassette-selling business flourished, and he invested in other businesses that made him millions.
Newscenta lists 5 things that show Dr. Osei Kwame Despite is rich.
Businesses
He also owns water production companies, insurance companies, microfinance companies, and banking companies.
Radio and TV stations
He owns Despite Firm Ltd, a trading company with a subsidiary in the media industry known as Despite Media.
The media house runs UTV, Peace FM, Okay FM, Neat FM, and Hello FM in Kumasi.
Mansions
Despite being the owner of a multi-million-dollar mansion located in Kumasi and East Legon in Accra. With all these companies in his possession, he is believed to be worth billions of dollars in liquid cash.
He owns a real estate company located in East Legon and Kumasi.
Fleet of expensive cars
The Ghanaian business tycoon, Dr. Osei Kwame Despite, has a love for very expensive automobiles, as seen in his collection of cars.
The multimillionaire has many vintage cars, which are very expensive, in his garage.
He has a Bugatti La Voiture Noire, a Rolls-Royce Sweptail, a Lamborghini Veneno Roadster, a Lykan HyperSport, and a Bugatti Chiron.
Philanthropic work
Last year, Dr. Osei Kwame Despite donated several items, including 500 cloths, 50 television sets, 500 bags of rice, 300 gallons of oil, 25 standing fans, 50 gas burners, 50 blenders, 25 tabletop fridges, 4 double-door fridges, and a cash donation of GH¢100,000 to 9 churches, the Islamic community, and the traditional authorities for people in his hometown of Wiamoase in the Ashanti Region.
The money and items are to be distributed to widows and orphans in Wiamoase.
In February 2023, on his birthday, Dr. Osei Kwame Despite and Dr. Ofori Sarpong donated $100,000 to the Komfo Anokye Teaching Hospital.
See the plush cars inside the Despite Automobile Museum@KwameDespiteGh pic.twitter.com/HgGH9OgtlN
— 𝓚𝓸𝓳𝓸 𝓝𝓮𝔀𝓼𝓖𝓗 (@KojoNewsgh) June 2, 2025
